The responsible conduct of research at UCT is supported through university-wide and faculty-specific policies, senate-level committees, and faculty-level research ethics committees (RECs):
- The RECs take responsibility for the review and oversight of research projects that engage with research participants through interactions and/or interventions, and/or use individually identifiable data about living individuals.
- Their work is shaped by core principles of justice, beneficence, and respect.
- RECs typically require detailed protocol information relating to:
- the reasonableness and minimisation of risks
- the balancing of risks and benefits associated with participation
- assurance as to the equitable representation of persons, and
- support for the voluntarism associated with ethics research.
- RECs also undertake special scrutiny of research that engages with vulnerable populations including, among others:
- children
- pregnant women and foetuses
- prisoners
- migrants, and
- people who are cognitively impaired.
- Faculty-level animal ethics committees (AECs) provide similar oversight for animal welfare and well-being in research projects ranging from laboratory research to wildlife-field studies.
Statement by the Senate Ethics in Research Committee on the review of Health Research
- All research conducted at the University of Cape Town (UCT), whether by academic or PASS staff members or students (both undergraduate and postgraduate), and post-doctoral fellows (hereafter: UCT community), which meets the definition of health research, must undergo review by a UCT research ethics committee (REC) registered with the National Health Research Ethics Council (NHREC).
- The review of health research must be done before any research activities (such as interviews or data collection) commence. Retrospective approval will not be granted.
- No health research may be conducted until written approval from an NHREC registered REC has been received.
UCT has 2 committees registered with the NHREC able to review Health Research:
- The Faculty of Health Sciences Human Research Ethics Committee (HREC), based in the Faculty of Health Sciences (FHS). Any research conducted by staff and students based in the FHS must be reviewed and approved by the HREC. Further information regarding their processes is available on their website, or via email to: hrec-enquiries@uct.ac.za.
- The Inter-Faculty Human Research Ethics Committee (IFHREC), serviced by the Office of Research Integrity. All staff and students who plan to conduct health research (as per the definition) and who are based in the Faculties of Commerce, Engineering and the Built Environment, Humanities and Law; the Centre for Higher Education and Development and the Graduate School of Business must submit their applications to the IFHREC. This includes staff in PASS departments who may be conducting health research. Further information regarding their processes is available on their website, or via email to: ifhrec.enquiries@uct.ac.za.
If there is in any doubt as to whether research constitutes health research, then a researcher must use the screening tool developed by the EiRC to determine which committee is most appropriate to review the proposed research. This tool may be accessed here.
Please note: this tool is currently being used as a pilot. If you have feedback or comments please send them to the
Guidelines and Standards
UCT Guidance
UCT Guideline for Risk-Based Ethical Review of Research (Human Participants)
Recommendations: Standard criteria for inclusion in research invitations
Statement by the Senate Ethics in Research Committee on review of Health Research
South African National Standards and Guidelines
PLEASE NOTE: The SANS10386:2021 is a restricted access document. It is only available to UCT staff and students and will require you to sign-in using your institutional credentials to view it. You cannot download or print the document.
Senate-level research ethics committees (RECs)
Human Subjects
- Senate Ethics in Research Committee (EiRC)
- Terms of Reference
- Standard Operating Procedure (SOP)
- Serviced by the Office of Research Integrity
- Inter-Faculty Human Research Ethics Committee (IFHREC)
- Visit website for Terms of Reference and other supporting information
Animal Subjects
- Senate Animal Ethics Committee (SAEC)
- Terms of Reference
- Serviced by the Office of Research Integrity
Faculty-level research ethics committees (RECs)
Human subjects
- Faculty of Health Sciences
- Faculty of Commerce
- Faculty of Law
- Faculty of Science
- Centre for Higher Education and Development
- Engineering and the Built Environment
- Graduate School of Business
Animal ethics
- Faculty of Health Sciences
- Faculty of Science: contact AEC Chair, Dr Ramona Hurdayal

For more information on research integrity contact the Office of Research Integrity